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Fibre synthesis equipment for straining flow spinning (SFS)
Where:
Center for Biomedical Technology
Ubicación:
Centro de Tecnología Biomédica (CTB)
Typology:
Infraestructura Científica
Manager: Gustavo Guinea
Email:
Production of high-performance biocompatible fibres with controlled properties. SFS is a versatile and accessible method of producing regenerated fibres (made with natural proteins) and bio-inspired fibres (made with recombinant proteins), in order to produce fibres that combine biocompatibility with superior mechanical performance.
Health, medicine, biomaterials, tissue engineering.
It allows fibres to be produced from fibroins and related proteins under a wide variety of conditions, resulting in biomaterials whose properties can be adapted to their applications. The fibres obtained can be modified by adding various biomolecules with biological activity, in order to modulate the organism¿s response to the material being implanted.
The fibres obtained offer a number of advantages when applied to biomedicine, even compared to the natural starting material. Those advantages include increased biocompatibility due to the elimination of possible contaminating molecules, the production of fibres with reproducible mechanical properties and the possibility of functionalising the fibres by using biomolecules with biological activity. The applications of these fibres include the treatment of tendon and ligament pathologies, which demand high mechanical performance in the short term, as well as maximum emphasis on biocompatibility and cellular interaction. This new combination of properties also makes it ideal for other applications in medicine, from sutures to bioactive structural biomaterial for cellular treatments and tissue engineering. Examples of use: graphene-doped fibre, fluorescent fibres, axon guidance, tissue scaffolding.
Technology patented by the UPM and the Universidad de Sevilla.
